By Howard Feldman
Authored by way of one of many world's major specialists at the administration of Alzheimer's sickness and similar dementias, this hugely illustrated atlas describes the colourful background of Alzheimer's ailment; its neuropathological foundation from structural mind imaging and autopsy experiences; and its devastating results on belief, cognition, conversation, and social habit. The booklet also will position nice emphasis at the more and more identifiable chance elements for improvement of the illness, with a view in the direction of prevention.
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Additional resources for Atlas of Alzheimer's Disease
A Canadian cohort study of cognitive impairment and related dementias (ACCORD): study methods and baseline results. Neuroepidemiology 2003; 22: 265–74. 8. Hamad AI, Ibrahim MA, Sulaiti EM. Dementia in Qatar. Saudi Med J 2004; 25: 79–82. 24. McMurtray A, Clark DG, Christine D, Mendez MF. Early-onset dementia: frequency and causes compared to late-onset dementia. Dement Geriatr Cogn Disord 2006; 21: 59–64. 9. Jellinger K. Prevalence of Alzheimer’s disease in very elderly people: a prospective neuropathological study.
Incidence of dementia and Alzheimer’s disease While a large number of prevalence studies on dementia have been done, especially in the developed world, incidence studies are less frequent, probably because they are much more costly to conduct. 6,33–40 The variation in the findings among different parts of the world, and sometimes even within a country, may be due to a number of reasons. There are methodologic differences, such as the different criteria used for diagnosing dementia, and the different data-collection and sampling methods.
44 These criteria have become the gold standard for diagnostic classification and provided the basis for clinical research in molecular biology, genetic analyses, and therapeutic interventions. Treatment Disease-modifying therapeutic strategies The past decade has seen the first approved treatments for the symptoms of AD. Acetylcholinesterase inhibitors (AChEIs) became available for public use between 1993 and 2002. Memantine, an uncompetitive N-methyl- The era of approved disease-modifying therapies for AD has not yet opened, but is being approached.
Atlas of Alzheimer's Disease by Howard Feldman